Academic Qualification

Ph.D. in Bioenvironmental Systems Engineering, National Taiwan University

MSc in Bioenvironmental Systems Engineering, National Taiwan University

BE in Bioenvironmental Systems Engineering, National Taiwan University

Teaching Area

Environmental DNA

Research Area

Environmental DNA

Marine Ecosystems

Environmental Biotechnology

Working Experience

Sep. 2025 ~ present, Assistant Professor, Department of Environmental Science Engineering, Faculty of Innovation Engineering, MUST

2024 ~ 2025, Postdoctoral Research Fellow in Department of Biology, Hong Kong Baptist University

2022 ~ 2024, Postdoctoral Research Fellow in State Key Laboratory of Marine Pollution, City University of Hong Kong

2022, Postdoctoral Research Fellow in Institute of Food Safety and Health, National Taiwan University

Academic Publication

1.          How, C.M., Ip, J.C., Deconinck, D., Zhao, M., Yan, M., Cheng, J., Leung, K.M.Y., Chan, L.L., Qiu, J., 2024. Refining sampling efforts for fish diversity assessment in subtropical urban estuarine and oceanic waters using environmental DNA with multiple primers. Environmental DNA 6, e70013.

2.          Kuo, Y.-H.1, How, C.M.1, Liao, V.H.-C., 2025. Sedimentary co-exposure to bis(2-ethylhexyl) phthalate and titanium dioxide nanoparticles aggravate ecotoxicity and ecological risks through disrupted bioenergetics in Caenorhabditis elegans. Marine Pollution Bulletin 212, 117515.

3.          How, C.M., Li, Y.-S., Huang, W.-Y., Wei, C.-C.*, 2024. Early-life exposure to mycotoxin zearalenone exacerbates aberrant immune response, oxidative stress, and mortality of Caenorhabditis elegans under pathogen Bacillus thuringiensis infection. Ecotoxicology and Environmental Safety 272, 116085.

4.          How, C.M., Cheng, K.-C., Li, Y.-S., Pan, M.-H., Wei, C.-C., 2023. Tangeretin supplementation mitigates the aging toxicity induced by dietary benzo[a]pyrene exposure with aberrant proteostasis and heat shock responses in Caenorhabditis elegans. Journal of Agricultural and Food Chemistry, 71, 13474–13482.

5.          How, C.M., Huang, C.-W., 2023. Dietary transfer of zinc oxide nanoparticles induces locomotive defects associated with GABAergic motor neuron damage in Caenorhabditis elegans. Nanomaterials 13, 289.

6.          How, C.M., Kuo, Y.-H., Huang, M.-L., Liao, V.H.-C., 2023. Assessing the ecological risk and ecotoxicity of the microbially mediated restoration of heavy metal-contaminated river sediment. Science of The Total Environment 858, 159732.

7.          How, C.M., Hsiu-Chuan Liao, V., 2022. Chronic exposure to environmentally relevant levels of di(2-ethylhexyl) phthalate (DEHP) disrupts lipid metabolism associated with SBP-1/SREBP and ER stress in C. elegans. Environmental Pollution 307, 119579.

8.          How, C.M., Lin, T.-A., Liao, V.H.-C., 2021. Early-life chronic di(2-ethylhexyl)phthalate exposure worsens age-related long-term associative memory decline associated with insulin/IGF-1 signaling and CRH-1/CREB in Caenorhabditis elegans. Journal of Hazardous Materials 417.

9.          How, C.M., Yen, P.-L., Wei, C.-C., Li, S.-W., Liao, V.H.-C., 2019. Early life exposure to di(2-ethylhexyl)phthalate causes age-related declines associated with insulin/IGF-1-like signaling pathway and SKN-1 in Caenorhabditis elegans. Environmental Pollution 251, 871–878.

10.      How, C.M., Li, S.-W., Liao, V.H.-C., 2018. Chronic exposure to triadimenol at environmentally relevant concentration adversely affects aging biomarkers in Caenorhabditis elegans associated with insulin/IGF-1 signaling pathway. Science of the Total Environment 640–641, 485–492.

11.      Wei, C.-C., How, C.M., Huang, C.-W., Huang, W.-Y., 2025. Long-term exposure to environmentally relevant concentrations of hexafluoropropylene oxide dimer acid (GenX) induces trans-generational motor deficits through H3K27 demethylase jmjd-1.2/PHF8 in Caenorhabditis elegans. Environmental Pollution 384, 126981.

12.      Wong, H.-C., How, C.M., Xi, L., Lin, C.-H., Chung, M.-T., Qiu, J.-W., Wong, C.K.-C., Su, K., Chiu, J.M.-Y., 2025. Comparative study of ontogenetic trophic transition in large yellow croaker from Hong Kong and Taiwan using metabarcoding and isotope analysis. Scientific Reports 15, 30120.

13.      Zhao, M.-H., Ip, J.C.-H., How, C.M., Li, Y.-X., Deconinck, D., Qiu, J.-W., 2025. DNA barcode reference database and gap analysis for biomonitoring Hong Kong’s marine animals. Regional Studies in Marine Science 81, 103946.

14.      Ip, J.C., Loke, H., Yiu, S.K.F., Zhao, M., Li, Y., Lin, Y., How, C.M., Mo, J., Yan, M., Cheng, J., Lai, V.C., Chan, L.L., Leung, K.M.Y., Qiu, J., 2024. Bottom trawling and multi‐marker eDNA metabarcoding surveys reveal highly diverse vertebrate and crustacean communities: a case study in an urbanized subtropical estuary. Environmental DNA 6, e70031.

15.      Jiang, J.-Y., How, C.M., Huang, C.-W., Luo, Y.-S., Wei, C.-C., 2024. Comparing the obesogenic effect and regulatory mechanisms of long-term exposure to per/polyfluoroalkyl substances with different terminal groups in Caenorhabditis elegans. Chemosphere 365, 143396.

16.      Yu, C.-W., Yen, P.-L., How, C.M., Kuo, Y.-H., Hsiu-Chuan Liao, V., 2024. Early-life long-term ibuprofen exposure reduces reproductive capacity involved in spermatogenesis impairment and associated with the transcription factor DAF-5 in Caenorhabditis elegans. Chemosphere 347, 140717.

17.      Seymour, M., Guibert, I., Jeunen, G., Hellström, M., Leray, M., Elbrect, V., Lau, A., Cutracci, M., How, C.M., Ip, J.C.H., Liu, Z., Moffitt, J., Qian, C., Qin, X., Tse, C.M., Wang, Y., Wang, Z., Zeng, X., Zhao, M., 2024. The First International eDNA Workshop in Hong Kong: A beginner’s guide for the next‐generation eDNA researcher. Environmental DNA 6, e552.

18.      Kuo, Y.-H., How, C.M., Huang, C.-W., Yen, P.-L., Yu, C.-W., Chang, C.-H., Liao, V.H.-C., 2023. Co-contaminants of ethinylestradiol and sulfamethoxazole in groundwater exacerbate ecotoxicity and ecological risk and compromise the energy budget of C. elegans. Aquatic Toxicology 257, 106473.

19.      Lin, T.-A., How, C.M., Yen, P.-L., Liao, V.H.-C., 2023. Sulfate-modified nanosized polystyrene impairs memory by inhibiting ionotropic glutamate receptors and the cAMP-response element binding protein (CREB) pathway in Caenorhabditis elegans. Science of The Total Environment 162404.

20.      Wei, C.-C., Li, S.-W., Wu, C.-T., How, C.M., Pan, M.-H., 2022. Dietary methylglyoxal exposure induces alzheimer’s disease by promoting amyloid β accumulation and disrupting autophagy in Caenorhabditis elegans. Journal of Agricultural and Food Chemistry 70, 10011–10021.

21.      Huang, C.-W., Liao, W.-R., How, C.M., Yen, P.-L., Wei, C.-C., 2021. Chronic exposure of zearalenone inhibits antioxidant defense and results in aging-related defects associated with DAF-16/FOXO in Caenorhabditis elegans. Environmental Pollution 285, 117233.

22.      Huang, Chi-Wei, Yen, P.-L., How, C.M., Chai, Z.Y., Liao, V.H.-C., 2021. Levels of bioavailable manganese in river sediment may elevate reproductive risk in model organism Caenorhabditis elegans. Aquatic Toxicology 239, 105958.

23.      Yen, P.-L., How, C.M., Hsiu-Chuan Liao, V., 2021. Early-life and chronic exposure to di(2-ethylhexyl) phthalate enhances amyloid-β toxicity associated with an autophagy-related gene in Caenorhabditis elegans Alzheimer’s disease models. Chemosphere 273, 128594.

24.      Huang, C.-W., Chai, Z.Y., Yen, P.-L., How, C.M., Yu, C.-W., Chang, C.-H., Liao, V.H.-C., 2020. The bioavailability and potential ecological risk of copper and zinc in river sediment are affected by seasonal variation and spatial distribution. Aquatic Toxicology 227, 105604.

25.      Li, S.-W., How, C.M., Liao, V.H.-C., 2018. Prolonged exposure of di(2-ethylhexyl) phthalate induces multigenerational toxic effects in Caenorhabditis elegans. Science of the Total Environment 634, 260–266.

26.      Cheng, Y.-H., Chou, W.-C., Yang, Y.-F., Huang, C.-W., How, C.M., Chen, S.-C., Chen, W.-Y., Hsieh, N.-H., Lin, Y.-J., You, S.-H., Liao, C.-M., 2018. PBPK/PD assessment for Parkinson’s disease risk posed by airborne pesticide paraquat exposure. Environmental Science and Pollution Research 25, 5359–5368.

27.      Cheng, Y.-H., Lin, Y.-J., You, S.-H., Yang, Y.-F., How, C.M., Tseng, Y.-T., Chen, W.-Y., Liao, C.-M., 2016. Assessing exposure risks for freshwater tilapia species posed by mercury and methylmercury. Ecotoxicology 25, 1181–1193.

28.      Yu, C.-W., How, C.M., Liao, V.H.-C., 2016. Arsenite exposure accelerates aging process regulated by the transcription factor DAF-16/FOXO in Caenorhabditis elegans. Chemosphere 150, 632–638.

Professional Certification and Awards

Hong Kong Research Grant Council Postdoctoral Fellowship Scheme 2024/2025 (HKBU 3-year fellowship)

The 1st eDNA Workshop in Hong Kong 2023 (HKU)

The Chung Hwa Rotary Scholarship 2019/2020

Academia Sinica Taiwan International Graduate Program Scholarship 2016-2018